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Mayo Clinic at AACC Annual Meeting and Clinical Lab Expo 2013

The American Association for Clinical Chemistry (AACC) Annual Meeting and Clinical Lab Expo is being held in Houston, Texas from July 28-August 1, 2013. Mayo Clinic has approximately 50 presenters at this year’s meeting. For your reference, information about Mayo Clinic presenters has been organized below. Visit the AACC Annual Meeting website for full event details.

Visit the Mayo Medical Laboratories as part of the Clinical Lab Expo at booth #5951.


Presenter(s) Title Date Time
Allan Jaffe, M.D. High Sensitivity Troponin Assays are Coming — How to Exploit the Benefits and Avoid the Pain 7/29/13 2:30 p.m. – 5:00 p.m.
Brad Karon, M.D., Ph.D. and Mark Ereth, M.D., M.A. Coagulation Analysis by Viscoelastography-Is There a Point-of-Care Clinical Appllication? 7/30/13 10:30 a.m. – 12:00 p.m.
Amy Saenger, Ph.D. Use and Misuse of Troponin Assays in Adult and Pediatric Hospitals 7/30/13 10:30 a.m. – Noon
Alicia Algeciras-Schimnich Ph.D. and Stefan Grebe, M.D., Ph.D. New Developments in Thyroid Cancer Diagnosis and Follow-up 7/31/13 2:30 p.m. – 5:00 p.m.

Short Courses

Paula Santrach, M.D., Bobbi Pritt, M.D. and Paul Kurtin, M.D.  Laboratory-Driven Testing Algorithms: A Strategy to Improve Ordering Accuracy, Efficiency, and Utilization 7/28/13 1:30-4:00 p.m.
Presenter(s) Title Date Time
Leslie Donato, Ph.D. Serum, Plasma, Arterial, Venous, Capillary? What Difference Does it Make? 7/30/13 10:30 a.m. – Noon
Paul Jannetto, Ph.D. A Laboratorians’ Guide to Performing Urine Drug Testing and Pharmacogenomics for Pain Management 7/30/13 10:30 a.m. – Noon
Darci Block, Ph.D. Non-Standard Body Fluid Testing: Reducing Risk and Avoiding Speed Bumps 7/31/13 10:30 a.m. – Noon
Melissa Snyder, Ph.D. Controversies in ANA and Celiac Disease Testing 7/31/13 2:30 p.m. – 5:00 p.m.


Presenter(s) Title Date Time
Darci Block, Ph.D. Data Driven Solutions for Common Pre-Analytical Problems 7/29/13 7:30 a.m. – 8:30 a.m.  12:30 p.m. – 1:30 p.m.
Leslie Donato, Ph.D. Macroenzymes: Diagnostic Dilemmas and Laboratory Solutions 7/29/13 7:30 a.m. – 8:30 a.m. 12:30 p.m. – 1:30 p.m.
Paul Jannetto, Ph.D. Taking the Pain Out of Pain Management 7/29/13 7:30 a.m. – 8:30 a.m
12:30 p.m. – 1:30 p.m.
Melissa Snyder, Ph.D. Utility of Allergen-Specific IgE Testing in Allergic Diseases 7/31/13 7:30 a.m. – 8:30 a.m
12:30 p.m. – 1:30 p.m.

Poster Abstracts

Time Title Presenter(s)
July 30
9:30am-5:00pm Cancer/Tumor Markers
Validation of a new highly sensitive thyroglobulin immunoassay (hTgsensitive) on the Thermo Scientific B·R·A·H·M·S KRYPTOR platform
E. Thomas1, A. Algeciras-Schimnich2, C. M. Preissner2. 1Research and Development, Thermofisher Scientific, Nîmes, France, 2Department of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, MN.
9:30am-5:00pm Nutrition/Trace Metals/Vitamins
Measurement of vitamin K1 (phylloquinone) in human serum by liquid chromatography-tandem mass spectrometry
D. M. Garby, R. DelRosso, L. A. Cheryk. Mayo Medical Laboratories, Andover, MA
9:30am-5:00pm Mass Spectrometry Applications
Infliximab measurement in serum using selective reaction monitoring LC-MS/MS
 M. A. V. Willrich, D. R. Barnidge, R. M. Karras, P. M. Ladwig, D. L. Murray, M. R. Snyder. Mayo Clinic, Rochester, MN
9:30am-5:00pm Mass Spectrometry Applications
Validation of a multiplex proteomic mass spectrometry method for identification of cerebrospinal fluid
 J. W. Meeusen, D. Barnidge, P. Ladwig, R. Karras, J. Katzmann, M. Snyder, D. Murray. Mayo Clinic, Rochester, MN
9:30am-5:00pm Endocrinology/Hormones
Establishment of Reference Intervals for Prolactin after Precipitation with Polyethyleneglycol and Detection of Macroprolactin
D. T. Meier, M. A. V. Willrich, D. R. Block, N. A. Baumann. Mayo Clinic, Rochester, MN
9:30am-5:00pm Endocrinology/Hormones
Detection of exogenous insulin use: Cross-reactivity of synthetic insulins in serum with commercial immunoassays and absolute determination using a mass spectrometric assay
 E. Kaleta1, A. Gorsh1, L. Ouverson1, M. Thevis2, R. Singh1. 1Department of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, MN, 2Institute of Biochemistry, Center for Preventative Doping Research, German Sport University, Cologne, Germany
9:30am-5:00pm Clinical Studies/Outcomes
High Serum Creatinine Variability Prior to Intravenous Contrast Medium Administration May Confound a Diagnosis of Contrast-Induced Nephropathy
 J. S. McDonald, R. J. McDonald, E. E. Williamson, D. F. Kallmes. Mayo Clinic, Rochester, MN
9:30am-5:00pm Clinical Studies/Outcomes
Proposing new analytic performance goals for immunoassay systems
 N. Akbas1, A. Algeciras-Schimnich1, N. A. Baumann1, D. R. Block1, J. R. Budd2, S. Gaston2, G. G. Klee1. 1Mayo Clinic, Rochester, MN, 2Beckman Coulter, Chaska, MN
9:30am-5:00pm Clinical Studies/Outcomes
Performance of flow cytometry to screen urine for bacteria and white blood cells prior to urine culture
 C. D. Giesen, A. M. Greeno, K. A. Thompson, R. Patel, S. M. Jenkins, J. C. Lieske. Mayo Clinic, Rochester, MN
9:30am-5:00pm Hematology/Coagulation
Measurement of zinc protoporphyrin and non-complexed protoporphyrin in human erythrocytes by liquid chromatography
 K. M. Kloke, M. J. Magera, P. A. Chezick, K. M. Raymond, S. Tortorelli. Mayo Clinic, Rochester, MN
9:30am-5:00pm Hematology/Coagulation
Intra-assay precision, inter-assay precision, and reliability of five platelet function methods used to monitor the effect of aspirin and clopidogrel on platelet function
 C. D. Koch, A. M. Wockenfus, R. S. Miller, N. V. Tolan, D. Chen, R. K. Pruthi, A. S. Jaffe, B. S. Karon. Mayo Clinic, Rochester, MN
July 31
9:30am-5:00pm Management
Improving patient care through test-utilization strategies for NTProBNP ordering practices in the inpatient setting
 E. Kaleta1, K. Scheele2, J. Patel2, A. Roy Hughes2, L. Pearson2, J. Hernandez2, C. Snozek2. 1Mayo Clinic, Rochester, MN, 2Mayo Clinic, Scottsdale, AZ
9:30am-5:00pm Point-of-Care Testing
Evaluation of three whole blood point of care lactate methods by comparison to plasma lactate and a laboratory developed whole blood flow-injection MS/MS method.
 N. V. Tolan1, A. M. Wockenfus1, C. D. Koch1, D. J. Dietzen2, B. S. Karon1. 1Mayo Clinic, Rochester, MN, 2St. Louis Children’s Hospital and Washington University School of Medicine, St. Louis, MO
9:30am-5:00pm Cardiac Markers
A comparison of a sensitive and two high-sensitivity cardiac troponin assays for diagnosing myocardial infarction after 90 minutes in the emergency setting
 P. Kavsak1, J. J. You1, S. Hill1, M. Oremus1, P. J. Devereaux1, A. S. Jaffe2, A. Worster1. 1McMaster University, Hamilton, ON, Canada, 2Mayo Clinic, Rochester, MN
9:30am-5:00pm Cardiac Markers
Differentiation of urinary thromboxane metabolites using LC-MS/MS explains the discordance with the AspirinWorks ELISA: implications for monitoring aspirin response
 N. V. Tolan, A. J. Lueke, C. K. Koch, A. V. Gray, A. S. Jaffe, B. S. Karon, A. K. Saenger. Mayo Clinic, Rochester, MN
9:30am-5:00pm Technology/Design Development
Validating accuracy of body fluid tests in the absence of a goldstandard method
 N. V. Voskoboev, C. D. Giesen, J. C. Lieske, J. J. Schilling, M. M. Hanley, S. J. Cambern, P. J. Jannetto, D. R. Block. Department of Laboratory Medicine and Pathology , Mayo Clinic, Rochester, MN
9:30am-5:00pm Technology/Design Development
Practical Approach to the Analytical Validation of Chemistry Testingin Body Fluids
 D. T. Meier, L. J. Ouverson, N. A. Baumann, D. R. Block. Mayo Clinic, Rochester, MN
9:30am-5:00pm Electrolytes/Blood Gas/Metabolites
Salicylate Interference with an Indirect ISE Method Causes Falsely Elevated Chloride Results
 R. M. Jackson, J. W. Meeusen, N. V. Tolan, J. H. Steuernagle, Q. Qian, B. S. Karon, P. J. Jannetto, D. R. Block, N. A. Baumann. Mayo Clinic, Rochester, MN
9:30am-5:00pm Pediatric/Fetal Clinical Chemistry
Amniotic fluid glucose provides superior sensitivity in identifying subclinical intra-amniotic infection compared with gram stain and bacterial culture
 J. W. Meeusen, L. J. Ouverson, N. A. Baumann, D. R. Block. Mayo Clinic, Rochester, MN
9:30am-5:00pm Lipids/Lipoproteins
Performance Evaluation of an Automated Assay for Lipoprotein-Associated Phospholipase A2 (Lp-PLA2) Activity
 H. Callanan, A. S. Jaffe, A. K. Saenger. Mayo Clinic, Rochester, MN
9:30am-5:00pm Lipids/Lipoproteins
Galectin-3 in Urine is a Promising Biomarker in Renal Fibrosis:  Assessment of Analytical Performance and Establishment of Reference Intervals Using Iothalamate Clearance Testing
 A. V. Gray, M. A. V. Willrich, A. D. Rule, J. C. Lieske, A. S. Jaffe, A. K. Saenger. Mayo Clinic, Rochester, MN
9:30am-5:00pm Lipids/Lipoproteins
Development of a LC-MS/MS Method to Quantitate Total and Fractionated Fecal Bile Acids
 A. J. Lueke, L. J. Donato, A. S. Jaffe, M. Camilleri, A. K. Saenger. Mayo Clinic Rochester, Rochester, MN
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