A recent study in the Brain journal, conducted by researchers in Mayo Clinic Jacksonville, evaluates the correspondence of Thal amyloid phase to Braak tangle stage and ante-mortem clinical characteristics in a large autopsy cohort and examines the relevance of Thal amyloid phase in a prospectively followed autopsied cohort who underwent ante-mortem.
Recent Stories for Research
Two fatal neurodegenerative diseases, frontotemporal dementia (FTD) and motor neuron disease (MND), demonstrate clinical, pathological, and genetic overlap. Hexanucleotide repeat expansions in chromosome 9 open reading frame 72 (C9ORF72) are causative for FTD and MND. In a recent study in Molecular Neurodegeneration, Mayo Clinic researchers set out to identify genetic modifiers of disease risk, age at onset, and survival after onset that may contribute to clinical variability.
Matrix-assisted laser desorption ionization time of flight (MALDI TOF) mass spectrometry (MS) is being rapidly embraced by laboratories around the globe for routine bacterial and fungal identification in clinical microbiology laboratories. A recent review in Clinical Chemistry, by Robin Patel, M.D., Chair of the Division of Clinical Microbiology at Mayo Clinic, discusses how MALDI-TOF MS provides rapid, accurate, and cost-effective identification of cultured bacteria and fungi.
Other Posts for Research
- Tailoring Research and Test Development to Reduce Mortality Risk of Endometrial Cancer
- Refining Individualized Medicine: Study Reduces Time to Deliver Treatment Plan for Melanoma Patients
- Evaluating Renal Cell Carcinoma Surveillance Guidelines
- The Effect of Murine Stem Cells for Interstitial Cells of Cajal on Colitis
- Renal Cell Carcinoma (RCC) with Rhabdoid Differentiation
- Clinical Applications of LC-MS Sex Steroid Assays
- Detection of Histoplasma capsulatum Antigen in Urine
- Predicting Cholangiocarcinoma in Patients With Primary Sclerosing Cholangitis
- Predicting Time to Transformation in Follicular Lymphoma
- ASXL1 and SETBP1 Mutations and Chronic Myelomonocytic Leukemia