PathWays Case Study: May 26

pathways052615-1pathways052615-2A 51-year-old woman presented with two rounded right upper-lobe lung nodules, measuring 3.0 cm and 0.2 cm in greatest dimension. She underwent wedge resection of the masses. Histologic sections revealed the tumor was composed of two cell populations. All neoplastic cells stained positively with TTF-1 and epithelial membrane antigen (EMA) immunohistochemistry, while the lining cells also stained positively with pan-cytokeratin.

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Melanie Bois, M.D.

Melanie Bois, M.D.
Resident, Division of Anatomic & Clinical Pathology
Mayo Clinic




Marie Christine Aubry, M.D.

Marie Christine Aubry, M.D.
Consultant, Division of Anatomic Pathology
Mayo Clinic
Professor of Laboratory Medicine and Pathology,
Mayo Clinic College of Medicine



April Josselyn

April Josselyn is a Marketing Associate at Mayo Medical Laboratories. She is the editor of Mayo Clinic PathWays and supports corporate communications strategies and internal communications. She has worked at Mayo Clinic since 2012. Outside of work, April enjoys the outdoors and being "hockey mom" for her two sports-crazed boys.


Excellent, as always.

Great case!

great case; thanks


nice case!

Thanks a lot for sharing this Cass

Great case…love the commentary on each option!!

I love the Mayo Clinic web site.

Many thanks for presenting this interesting case.

Great case! And thanks for the update regarding the new nomenclature.

wonderful case thanks for efforts.

Thank you

Excellent differential diagnosis thank you

I got benefit thank you

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