PathWays Case Study: August 11


081115-2 A 52-year-old man presented with diarrhea and abdominal pain. He was found to have a large (12 cm) ulcerative rectosigmoid mass and died of the tumor less than two months after symptoms were developed.  At autopsy, the tumor had metastasized to the liver and lymph nodes (pericolic, small bowel mesenteric, and paraaortic). The photomicrographs show H&E stain and INI–1 immunochemistry.

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Hee Eun Lee, M.D., Ph.D.

Hee Eun Lee, M.D., Ph.D.
Resident, Anatomic and Clinical Pathology
Mayo Clinic





Thomas Smyrk, M.D.

Thomas Smyrk, M.D.
Consultant, Division of Anatomic Pathology
Mayo Clinic
Professor of Laboratory Medicine and Pathology,
Mayo Clinic College of Medicine





April Josselyn

April Josselyn is a Marketing Associate at Mayo Medical Laboratories. She is the editor of Mayo Clinic PathWays and supports corporate communications strategies and internal communications. She has worked at Mayo Clinic since 2012. Outside of work, April enjoys the outdoors and being "hockey mom" for her two sports-crazed boys.


So the difference between proximal-type epithelioid sarcoma and INI-1 negative rhabdoid carcinoma was established in this case on clinical setting, isn’t it ?


Rare case.

Unfortunately, our expertise is poorly helpfull for the pacient.


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