Adipokines induce inflammation and trigger carcinogenesis by various pathways. Research on cancer associated adipocytes (CAA) indicates that they undergo functional changes to a pro inflammatory state that promotes tumorigenesis. As the incidence of steatohepatitis increases world wide ,more work is necessary on the role of adipocytokines in the pathogenesis of SH-HCC. There are multiple , interconnected pathways that link adipocytokines in their microenvironment to cancer stem cells and tumor immunology It also means that early identification of steatohepatitis is necessary as a preventive measure