Mayo Clinic Laboratory and Pathology Research Roundup: April 25

The Research Roundup provides an overview of the past week’s research from Mayo Medical Laboratories consultants, including a featured article of the week, abstracts, and complete list of published studies and reviews.

Featured Study of the Week

Consortium Study of Dohner Hierarchical Classification of Chronic Lymphocytic Leukemia Reveals Improved Survival

Leukemia-960x540Back in 2000, a German study guided by Hartmut Dohner, M.D., established the prognostic association of chromosome abnormalities identified by fluorescence in situ hybridization (FISH) analysis in patients with chronic lymphocytic leukemia (CLL). Since then, the “Dohner hierarchical classification” has been the gold standard by which clinicians in both academic and community settings treat and counsel their CLL patients. Now, more than 15 years later, a multi-institutional study, led by Mayo Clinic, revisited the Dohner hierarchy. Why? To learn if the original prognostic association still holds true. According to the new study, published in the British Journal of Haematology, this FISH hierarchy has indeed stood the test of time. Further, overall survival is now significantly longer in CLL patients—at least partly due to improved therapeutic options.

Published to PubMed This Week


Kelley Schreiber

Kelley Schreiber is a Marketing Channel Manager at Mayo Medical Laboratories. She is the principle editor and writer of Insights and leads social media and direct marketing strategy. Kelley has worked at Mayo Clinic since 2013. Outside of work, you can find Kelley running, traveling, playing with her new kitten, and exploring new foods.


This appears to be great news for CLL. I was diognosis aprox. 5 years ago with non symptomatic CLL and came across Mayo’s Clinical trials with ECGC along with post on their blog. Since I have been changed my diet somewhat , drink Green Tea and take ECGC , TUMERAC/ CUMICUM AND VITIMAN D3. I am currently 70 years old and have a follow up with my Doc. every 6 months at UF Health in Gainesville, Florida. My wife sees Dr. Jaeckle at Mayo in Jacksonville, Florida every three months following a confinement of 13 days at UFHEALTH-TENA that almosteoporosis crippled he and since there has been a marked improvement. She has another apt at Mayo in May and I’m considering asking for a referral for another opinion.

Aubrey Rogers

and……This is just another reason why I trust the Mayo Clinic for my family’s healthcare needs. The words Thank You do not seem adequate enough to express my gratitude…

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