PathWays Case Study for April 26



A 90-year-old man with symptomatic severe aortic stenosis underwent elective percutaneous (transcatheter) native aortic valve replacement with a bovine bioprosthetic valve. Immediately following the procedure, the patient became hemodynamically unstable, developed a large femoral hematoma at the site of catheterization, and a large prosthetic valve mass was noted on echocardiogram. Despite supportive measures, the patient continued to deteriorate and expired approximately 12 hours following the procedure. An autopsy was performed.

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Charles Leduc, M.D., C.M.
Resident, Cardiovascular Pathology
Mayo Clinic





Dr. Joseph Maleszewski

Joseph Maleszewski, M.D.
Consultant, Division of Anatomic Pathology
Mayo Clinic
Associate Professor of Laboratory Medicine and Pathology and Associate Professor of Medicine,
Mayo Clinic College of Medicine
Follow him on Twitter: @joemaleszewski


April Josselyn

April Josselyn is a Marketing Associate at Mayo Medical Laboratories. She is the editor of Mayo Clinic PathWays and supports corporate communications strategies and internal communications. She has worked at Mayo Clinic since 2012. Outside of work, April enjoys the outdoors and being "hockey mom" for her two sports-crazed boys.


This is a rare complication in my experience

What does the CM stand for after the name of Charles LeDuc M.D. C.M.? Please respond by email. Thank you.

my mother underwent pci to place a stent in LAD artery she had an acute MI within first 24 hours after the procedure which was proved to be in LAD teritorry by echocardiography.was it due to the slow drug releasing stent as described by the cardiologist ?the pathogenesis might be the same as in this case?

In Canada, a medical school is a faculty or school of a university that trains would-be medical doctors and usually offers a three- to five-year Doctor of Medicine (M.D.) or Doctor of Medicine and Master of Surgery (M.D., C.M.) degree. Although presently most students enter medicine having previously earned another degree, the M.D. is technically considered an undergraduate degree in Canada.

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