The patient is a 45-year-old man who presented with renal vein thrombosis requiring urgent anti-coagulation. His serum creatinine was 1.1 mg/dL with an albumin of 3.2 g/dL. No monoclonal proteins were detected on serum protein electrophoresis. Cryoglobulins and cryofibrinogens were negative. C3 was elevated at 181 mg/dL and C4 was normal at 29 mg/dL. ANA and Anti-ds DNA were negative. Quantitative urinalysis shows a total protein of 3665 mg/24 hour.
Pingchuan Zhang, B.M.
Resident, Renal Pathology
Mariam (Priya) Alexander, M.D.
Consultant, Division of Anatomic Pathology
Assistant Professor of Laboratory Medicine and Pathology,
Mayo Clinic College of Medicine