Mayo Clinic Laboratory and Pathology Research Roundup: Oct. 10

The Research Roundup provides an overview of the past week’s research from Mayo Medical Laboratories consultants, including featured abstracts and complete list of published studies and reviews.


Featured Abstract

Noninvasive Assessment of Renal Fibrosis with Magnetization Transfer MR Imaging: Validation and Evaluation in Murine Renal Artery Stenosis

woman-in-a-laboratory-looking-through-a-microscope-16-x-9Mayo Clinic researchers conducted a study to test the utility of magnetization transfer imaging in detecting and monitoring the progression of renal fibrosis in mice with unilateral renal artery stenosis. In the stenotic kidney, the median magnetization transfer ratio showed progressive increases from baseline to six weeks after surgery, which were accompanied by a progressive loss in renal volume, perfusion, blood flow, and oxygenation. Based on the results, magnetization transfer imaging was used successfully to measure and longitudinally monitor the progression of renal fibrosis in mice with unilateral renal artery stenosis. The study was published in Radiology


Published to PubMed This Week

brentwestra

Brent Westra

Brent Westra is a Marketing Segment Manager at Mayo Medical Laboratories. He leads marketing strategies for product management and specialty testing along with new media innovations. Brent has worked at Mayo Clinic since 2011.