PathWays Case Study: October 10

A 58-year-old Caucasian male was found dead in the cab of a vehicle that was slightly crashed into a barn. Past medical history includes obesity, poorly controlled type 2 diabetes, and tobacco use. Autopsy revealed no trauma, hilar and mediastinal lymphadenopathy (Figure 1), heart (cardiomegaly, 611 g) with no mottling or fibrosis, and mild coronary artery disease (Figure 2). Other organ systems were grossly normal, including lungs and liver (Figure 3). Negative toxicology studies. Histology is shown (Figures 4 to 8).

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Alessia Buglioni, M.D.
Resident, Anatomic and Clinical Pathology
Mayo Clinic



Mariam (Priya) Alexander, M.D.Mariam (Priya) Alexander, M.D.
Consultant, Division of Anatomic Pathology
Mayo Clinic
Associate Professor of Laboratory Medicine and Pathology,
Mayo Clinic College of Medicine and Science



April Josselyn

April Josselyn is a Marketing Associate at Mayo Medical Laboratories. She is the editor of Mayo Clinic PathWays and supports corporate communications strategies and internal communications. She has worked at Mayo Clinic since 2012. Outside of work, April enjoys the outdoors and being "hockey mom" for her two sports-crazed boys.


Very good case, and always nice to find the cause of death. One of my very first cases as a resident had this process, and I remarked that the cardiac slices didn’t look like an MI. My consultant on that day, Dr. JTL, told me “If it doesn’t look like an MI, it probably isn’t !”. How true. Thanks!

An excellent case! A similar one I had had years ago during my training:-)

A great case!
Similar to one of my autopsy cases I was involved during my residency training!
Well done!

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