Genetics

This week’s Research Roundup highlights multifaceted Fanconi anemia signaling.

By Kelley Schreiber • January 1, 2018

Researchers at Mayo Clinic have discovered a second-tier test for Pompe disease that has been shown to improve the specificity of newborn screening for the disorder, which would lower the rate of false-positive results.

By April Josselyn • December 22, 2017

Originally presented November 8, 2017
The “Specialty Testing” webinar will briefly cover the current knowledge concerning the molecular genetic classification of adult gliomas.

By MML Education • December 1, 2017

Hutton Kearney, Ph.D., Consultant of Hereditary Genomics Laboratory in the Division of Laboratory Genetics and Genomics at Mayo Clinic, participated in an interview with Frontline Genomics Magazine to discuss cytogenetics.

By Kelley Schreiber • November 24, 2017

On the October 28 broadcast of Mayo Clinic Radio, Myra Wick, M.D., Ph.D., Consultant in the Division of Laboratory Genetics and Genomics at Mayo Clinic, explains the latest advances in prenatal screening.

By Kelley Schreiber • November 10, 2017

Ann Moyer, M.D., Ph.D., discusses an additional gene, NUDT15, which is important in the prediction of thiopurine-related toxicity This gene has been added to our TPMT genotyping assay available through Mayo Medical Laboratories.

By Mayo Medical Laboratories • October 25, 2017

Ann Moyer, M.D., Ph.D., discusses the importance of pharmacogenomics testing to limit adverse drug reactions and the new focused pharmacogenomics panel available through Mayo Medical Laboratories.

By Mayo Medical Laboratories • October 23, 2017

In this month’s “Hot Topic,” D. Jane Hata, Ph.D., provides an overview of the epidemiology of Zika virus, as well as the possible clinical features of disease and the recommended laboratory tests to assist in the diagnosis of Zika virus infection.

By Jane Hata, Ph.D. • September 18, 2017

Devin Oglesbee, Ph.D., Director of the Biochemical and Molecular Genetics Laboratories at Mayo Clinic, provides an overview of the lysosomal storage disease panel, when it is appropriate to order this test, what actions the results allow you to take, and how this test improves upon previous approaches.

By Mayo Medical Laboratories • September 6, 2017

Gessi Bentz Pino, CGS, a Genetic Counselor in the Department of Laboratory Medicine and Pathology at Mayo Clinic, provides an overview of the lysosomal storage disorders screen, when it is appropriate to order this test, what actions the results allow you to take, and how this test improves upon previous approaches.

By Mayo Medical Laboratories • August 4, 2017

A recent Huff Post article, authored by the Mayo Clinic Center for Individualized Medicine, highlights three genetics tests to improve prenatal screening, including Mayo Medical Laboratories’ cell-free DNA prenatal screen.

By Kelley Schreiber • July 28, 2017

Newborn screening panels (that test for a variety of conditions) are available in every state; however, test performance and response rate by each state is very different. Mayo Clinic’s Biochemical Genetics Laboratory created the Collaborative Laboratory Integrated Reports tool to mitigate the national (and international) problem of false positives and to raise the bar on test performance.

By Christoph Bahn • July 24, 2017

Mayo Clinic has launched a first-of-its-kind clinical test that will be used to help patients who may be at a diagnostic “dead end” with other genetic testing. The mate-pair sequencing test can identify chromosome alterations or “breakpoints” involved in chromosome rearrangements, pinpointing the precise genes involved.

By Gina Chiri-Osmond • May 12, 2017