Research

This week’s Research Roundup highlights how CDK4/6-dependent activation of DUB3 regulates cancer metastasis through SNAIL1.

By Kelley Schreiber • January 16, 2017

This week’s Research Roundup highlights that genomic analysis reveals frequent TRAF7 mutations in intraneural perineuriomas.

By Kelley Schreiber • January 9, 2017

Endometrial cancer triggers remain elusive, despite continued research. But given the typical inflammatory profile in these cases, microbes in the uterine environment are suspected to play a role in the development of this disease. To probe the microbes directly within the uterine environment and examine how these microbes could influence cancer within the endometrial lining, Mayo researchers conducted the first direct assessment uterine microbiome study published in Genome Medicine.

By Mayo Clinic News Network • January 6, 2017

This week’s Research Roundup highlights differential gene expression profiling of matched primary renal cell carcinoma and metastases, revealing upregulation of extracellular matrix genes

By Kelley Schreiber • December 26, 2016

This week’s Research Roundup highlights the development of a microscopic colitis disease activity index.

By Kelley Schreiber • December 19, 2016

This week’s Research Roundup highlights clear cell Type A and B molecular subtypes in metastatic clear cell renal cell carcinoma, identifying tumor heterogeneity and aggressiveness.

By Kelley Schreiber • December 12, 2016

Researchers at Mayo Clinic’s campus in Florida have conducted the world’s first prospective, blinded, and placebo-controlled clinical study to test the benefit of using bone marrow stem cells, a regenerative medicine therapy, to reduce arthritic pain and disability in knees.

By Mayo Clinic News Network • December 9, 2016

This week’s Research Roundup highlights the presence of intraepithelial food antigen in patients with active eosinophilic oesophagitis.

By Kelley Schreiber • December 5, 2016

This week’s Research Roundup highlights that there is no difference between latiglutenase and a placebo in reducing villous atrophy or improving symptoms in patients with symptomatic celiac disease.

By Kelley Schreiber • November 28, 2016

Researchers at Mayo Clinic Center for Individualized Medicine have discovered a potential cause and a promising new treatment for inflammatory myofibroblastic tumors, a rare soft tissue cancer that does not respond to radiation or chemotherapy.

By Mayo Clinic News Network • November 25, 2016

This week’s Research Roundup highlights common and extremely large fragile sites are targets for human papillomavirus integrations and chromosome rearrangements in oropharyngeal squamous cell carcinoma.

By Kelley Schreiber • November 21, 2016

This week’s Research Roundup highlights hepatosplenic T-cell lymphoma with blastoid morphology in a patient with Crohn disease.

By Kelley Schreiber • November 14, 2016

This week’s Research Roundup highlights chromoplectic TPM3-ALK rearrangement in a patient with inflammatory myofibroblastic tumor.

By Kelley Schreiber • November 7, 2016