Research Archives - Insights

This week’s Research Roundup highlights how AKT-phosphorylated FOXO1 suppresses ERK activation and chemoresistance by disrupting IQGAP1-MAPK interaction.

By Kelley Schreiber • March 20, 2017

This week’s Research Roundup highlights the clinical and pathological evolution of giant cell arteritis with a prospective study of follow-up temporal artery biopsies in 40 treated patients.

By Kelley Schreiber • March 13, 2017

Mayo Clinic researchers have found that an experimental drug, LCL161, stimulates the immune system, leading to tumor shrinkage in patients affected by multiple myeloma. The findings are published in Nature Medicine.

By Mayo Clinic News Network • March 9, 2017

This week’s Research Roundup highlights outcomes of warfarin therapy for bioprosthetic valve thrombosis of surgically implanted valves.

By Kelley Schreiber • March 6, 2017

This week’s Research Roundup highlights how cellular senescence mediates fibrotic pulmonary disease.

By Kelley Schreiber • February 27, 2017

A Mayo Clinic study has shown evidence linking the biology of aging with idiopathic pulmonary fibrosis, a disease that impairs lung function and causes shortness of breath, fatigue, declining quality of life, and, ultimately, death.

By Mayo Clinic News Network • February 24, 2017

This week’s Research Roundup highlights pathogenic implications of cerebrospinal fluid barrier pathology in neuromyelitis optica.

By Kelley Schreiber • February 20, 2017

This week’s Research Roundup highlights measurements and models of electric fields in the in vivo human brain during transcranial electric stimulation.

By Kelley Schreiber • February 13, 2017

This week’s Research Roundup highlights alterations in the immune cell composition in premalignant breast tissue that precede breast cancer development.

By Kelley Schreiber • February 6, 2017

This week’s Research Roundup highlights thyroid hormone treatment among pregnant women with subclinical hypothyroidism.

By Kelley Schreiber • January 30, 2017

This week’s Research Roundup highlights renal cell carcinoma with isolated lymph node involvement, identifying long-term natural history and predictors of oncologic outcomes following surgical resection.

By Kelley Schreiber • January 23, 2017

This week’s Research Roundup highlights how CDK4/6-dependent activation of DUB3 regulates cancer metastasis through SNAIL1.

By Kelley Schreiber • January 16, 2017

This week’s Research Roundup highlights that genomic analysis reveals frequent TRAF7 mutations in intraneural perineuriomas.

By Kelley Schreiber • January 9, 2017