Endometrial cancer triggers remain elusive, despite continued research. But given the typical inflammatory profile in these cases, microbes in the uterine environment are suspected to play a role in the development of this disease. To probe the microbes directly within the uterine environment and examine how these microbes could influence cancer within the endometrial lining, Mayo researchers conducted the first direct assessment uterine microbiome study published in Genome Medicine.
This week’s Research Roundup highlights differential gene expression profiling of matched primary renal cell carcinoma and metastases, revealing upregulation of extracellular matrix genes
This week’s Research Roundup highlights clear cell Type A and B molecular subtypes in metastatic clear cell renal cell carcinoma, identifying tumor heterogeneity and aggressiveness.
Researchers at Mayo Clinic’s campus in Florida have conducted the world’s first prospective, blinded, and placebo-controlled clinical study to test the benefit of using bone marrow stem cells, a regenerative medicine therapy, to reduce arthritic pain and disability in knees.
This week’s Research Roundup highlights the presence of intraepithelial food antigen in patients with active eosinophilic oesophagitis.
This week’s Research Roundup highlights that there is no difference between latiglutenase and a placebo in reducing villous atrophy or improving symptoms in patients with symptomatic celiac disease.
Researchers at Mayo Clinic Center for Individualized Medicine have discovered a potential cause and a promising new treatment for inflammatory myofibroblastic tumors, a rare soft tissue cancer that does not respond to radiation or chemotherapy.
This week’s Research Roundup highlights common and extremely large fragile sites are targets for human papillomavirus integrations and chromosome rearrangements in oropharyngeal squamous cell carcinoma.
This week’s Research Roundup highlights chromoplectic TPM3-ALK rearrangement in a patient with inflammatory myofibroblastic tumor.