A Mayo Clinic study has shown evidence linking the biology of aging with idiopathic pulmonary fibrosis, a disease that impairs lung function and causes shortness of breath, fatigue, declining quality of life, and, ultimately, death.
This week’s Research Roundup highlights pathogenic implications of cerebrospinal fluid barrier pathology in neuromyelitis optica.
This week’s Research Roundup highlights measurements and models of electric fields in the in vivo human brain during transcranial electric stimulation.
This week’s Research Roundup highlights alterations in the immune cell composition in premalignant breast tissue that precede breast cancer development.
This week’s Research Roundup highlights renal cell carcinoma with isolated lymph node involvement, identifying long-term natural history and predictors of oncologic outcomes following surgical resection.
Endometrial cancer triggers remain elusive, despite continued research. But given the typical inflammatory profile in these cases, microbes in the uterine environment are suspected to play a role in the development of this disease. To probe the microbes directly within the uterine environment and examine how these microbes could influence cancer within the endometrial lining, Mayo researchers conducted the first direct assessment uterine microbiome study published in Genome Medicine.
This week’s Research Roundup highlights differential gene expression profiling of matched primary renal cell carcinoma and metastases, revealing upregulation of extracellular matrix genes
This week’s Research Roundup highlights clear cell Type A and B molecular subtypes in metastatic clear cell renal cell carcinoma, identifying tumor heterogeneity and aggressiveness.
Researchers at Mayo Clinic’s campus in Florida have conducted the world’s first prospective, blinded, and placebo-controlled clinical study to test the benefit of using bone marrow stem cells, a regenerative medicine therapy, to reduce arthritic pain and disability in knees.